Frequently Asked Questions (FAQs)

REGISTER FOR C.L.I.M.B.® TRAINING
General Questions
What is C.L.I.M.B.®?
The C.L.I.M.B.® (Continuum of Learning to Improve Management with Botulinum Toxin) injector training platform is a multi-tiered learning continuum designed to educate physicians with every level of experience with botulinum toxin therapy. C.L.I.M.B.® can help physicians improve their clinical skills involving the appropriate use of Dysport for the benefit of both their practices and their patients.
How can C.L.I.M.B.® help me and my practice?
The C.L.I.M.B.® training program is a great professional introduction to administering Dysport, starting with a variety of one-on-one and virtual injection training options; materials to assist your office and patients—clinical information, patient support information, and a Resource guide to ordering and reimbursement; and the opportunity to register on our Doctor Locator app, which will be available on the dysport.com patient site, to provide patients with your contact information plus your professional background if you qualify
What is Dysport?
Dysport is an injectable form of botulinum toxin type A (BoNT-A), which is isolated and purified from Clostridium bacteria. It is supplied as a lyophilized powder. Dysport has approved indications in the United States for the treatment of adult cervical dystonia and for the treatment of adult spasticity. Dysport is also the first and only FDA-approved botulinum toxin for the treatment of lower limb spasticity in pediatric patients 2 years of age and older. Visit www.Dysport.com to learn more.
What is IPSEN CARES®?
IPSEN CARES® (Coverage, Access, Reimbursement, & Education Support) is dedicated to ensuring patients, providers, and caregivers have the resources needed to help access the Ipsen medications that are critical to managing their/their patients' conditions. IPSEN CARES® is staffed Monday to Friday by experts who can assist with a broad range of medical, educational, logistical, and coverage information regarding Ipsen medicines. Involving the entire treatment team that surrounds patients on a daily basis, IPSEN CARES® can provide benefits verification (research of a patient’s medical or pharmacy benefit insurance coverage), prior authorization information, a patient assistance program (free medications for qualified uninsured patients), co-pay assistance programs for eligible patients, billing and coding support, and coordination with specialty pharmacies. Additional information is also available by visiting http://www.ipsencares.com.
What is the Training & Resources section?
Each Dysport indication page contains all the drug, dosing, and treatment information you will need after you’ve completed the C.L.I.M.B.® training program—videos on reconstitution and mechanism of action, monograph, injection tracker, plus extensive support materials, including a patient brochure, copay, and financial assistance information, plus a Resources brochure to help expedite ordering and reimbursement.
What is the Dysport Doctor Locator?
The Dysport Doctor Locator is a directory of physicians who have notified Ipsen Biopharmaceuticals that they are injecting Dysport and have received the necessary training from Ipsen and have experience in injecting. You can list your contact information, directions to your office, and area of specialization for potential patients. Inclusion of a qualifying physician in the Doctor Locator does not constitute a referral, recommendation, endorsement, or verification of credentials, qualifications, or abilities of the physician listed. Conversely, the absence of a physician's name and information should not be construed as a negative comment from Ipsen Biopharmaceuticals about the physician's credentials, qualifications, or abilities. Ipsen Biopharmaceuticals disclaims and shall not be liable for any harm caused to patients resulting from reliance on the information contained in the Dysport Doctor Locator or the treatment provided by any doctor listed in the Dysport Doctor Locator.
What is "Find a Dysport Trainer"?
“Find a Dysport Trainer” helps you locate the nearest professionally trained Dysport instructor.
Account Questions
How do I create an account?
It’s easy. Go to the home page and click or tap on the “REGISTER FOR C.L.I.M.B.® TRAINING” button.
What if I forget my password?
Go to the Reset Password page here and enter your email. Once you submit, you will be sent an email with a link to reset your password.
Dysport Doctor Locator Questions
How do I sign up for the Dysport Doctor Locator?
Signing up for the Dysport Doctor Locator requires you to have registered for and taken the injection training modules of the C.L.I.M.B.® training program. You must have successfully injected Dysport. You can either sign up for the Dysport Doctor Locator when you are registering for C.L.I.M.B.® or sign up at a later time. In order to qualify, you must have experience in injecting Dysport.
How do I change my information on the Dysport Doctor Locator?
Click on the “Sign In” button on the top navigation bar. After you sign in to your account, you will see a “My Account” link on the top navigation that you can click. Once on your Account page, you will see an “Edit” button on which you can click or tap to change your information. Once you save that information, your updates will be submitted for reapproval.
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Important Safety Information

Warning: Distant Spread of Toxin Effect

Postmarketing reports indicate that the effects of Dysport® (abobotulinumtoxinA) and all botulinum toxin products may spread from the area of injection to produce symptoms consistent with botulinum toxin effects. These may include asthenia, generalized muscle weakness, diplopia, blurred vision, ptosis, dysphagia, dysphonia, dysarthria, urinary incontinence, and breathing difficulties. These symptoms have been reported hours to weeks after injection. Swallowing and breathing difficulties can be life threatening and there have been reports of death. The risk of symptoms is probably greatest in children treated for spasticity, but symptoms can also occur in adults treated for spasticity and other conditions, particularly in those patients who have underlying conditions that would predispose them to these symptoms. In unapproved uses, including upper limb spasticity in children, and in approved indications, cases of spread of effect have been reported at doses comparable to or lower than the maximum recommended total dose.

Contraindications

Dysport is contraindicated in patients with known hypersensitivity to any botulinum toxin preparation or to any of the components; or in the presence of infection at the proposed injection site(s); or in patients known to be allergic to cow’s milk protein. Hypersensitivity reactions including anaphylaxis have been reported.

Warnings and Precautions

Lack of Interchangeability Between Botulinum Toxin Products

The potency Units of Dysport are specific to the preparation and assay method utilized. They are not interchangeable with other preparations of botulinum toxin products, and, therefore, units of biological activity of Dysport cannot be compared to or converted into units of any other botulinum toxin products assessed with any other specific assay method.

Dysphagia and Breathing Difficulties

Treatment with Dysport and other botulinum toxin products can result in swallowing or breathing difficulties. Patients with pre-existing swallowing or breathing difficulties may be more susceptible to these complications. In most cases, this is a consequence of weakening of muscles in the area of injection that are involved in breathing or swallowing. When distant side effects occur, additional respiratory muscles may be involved. Deaths as a complication of severe dysphagia have been reported after treatment with botulinum toxin. Dysphagia may persist for several weeks, and require use of a feeding tube to maintain adequate nutrition and hydration. Aspiration may result from severe dysphagia and is a particular risk when treating patients in whom swallowing or respiratory function is already compromised. Patients treated with botulinum toxin may require immediate medical attention should they develop problems with swallowing, speech, or respiratory disorders. These reactions can occur within hours to weeks after injection with botulinum toxin.

Pre-existing Neuromuscular Disorders

Individuals with peripheral motor neuropathic diseases, amyotrophic lateral sclerosis, or neuromuscular junction disorders (e.g., myasthenia gravis or Lambert-Eaton syndrome) should be monitored particularly closely when given botulinum toxin. Patients with neuromuscular disorders may be at increased risk of clinically significant effects including severe dysphagia and respiratory compromise from typical doses of Dysport.

Human Albumin and Transmission of Viral Diseases

This product contains albumin, a derivative of human blood. Based on effective donor screening and product manufacturing processes, it carries an extremely remote risk for transmission of viral diseases and variant Creutzfeldt-Jakob disease (vCJD). There is a theoretical risk for transmission of Creutzfeldt-Jakob disease (CJD), but if that risk actually exists, the risk of transmission would also be considered extremely remote. No cases of transmission of viral diseases, CJD, or vCJD have ever been identified for licensed albumin or albumin contained in other licensed products.

Intradermal Immune Reaction

The possibility of an immune reaction when injected intradermally is unknown. The safety of Dysport for the treatment of hyperhidrosis has not been established. Dysport is approved only for intramuscular injection.

Most Common Adverse Reactions

Adults with upper limb spasticity (≥2% and greater than placebo): nasopharyngitis, urinary tract infection, muscular weakness, musculoskeletal pain, dizziness, fall, and depression.

Adults with lower limb spasticity (≥5% and greater than placebo): falls, muscular weakness, and pain in extremity.

Adults with cervical dystonia (≥5% and greater than placebo): muscular weakness, dysphagia, dry mouth, injection site discomfort, fatigue, headache, musculoskeletal pain, dysphonia, injection site pain, and eye disorders.

Pediatric patients with lower limb spasticity (≥10% and greater than placebo): upper respiratory tract infection, nasopharyngitis, influenza, pharyngitis, cough, and pyrexia.

Drug Interactions

Co-administration of Dysport and aminoglycosides or other agents interfering with neuromuscular transmission (e.g., curare-like agents), or muscle relaxants, should be observed closely because the effect of botulinum toxin may be potentiated. Use of anticholinergic drugs after administration of Dysport may potentiate systemic anticholinergic effects, such as blurred vision. The effect of administering different botulinum neurotoxins at the same time or within several months of each other is unknown. Excessive weakness may be exacerbated by another administration of botulinum toxin prior to the resolution of the effects of a previously administered botulinum toxin. Excessive weakness may also be exaggerated by administration of a muscle relaxant before or after administration of Dysport.

Use in Pregnancy

Based on animal data, Dysport may cause fetal harm. There are no adequate and well-controlled studies in pregnant women. Dysport should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.

Pediatric Use

Based on animal data Dysport may cause atrophy of injected and adjacent muscles; decreased bone growth, length, and mineral content; delayed sexual maturation; and decreased fertility.

Geriatric Use

In general, elderly patients should be observed to evaluate their tolerability of Dysport, due to the greater frequency of concomitant disease and other drug therapy. Subjects aged 65 years and over who were treated with Dysport for lower limb spasticity reported a greater percentage of fall and asthenia as compared to those younger (10% vs 6% and 4% vs 2%, respectively).

To report SUSPECTED ADVERSE REACTIONS or product complaints, contact Ipsen at 1-855-463-5127. You may also report SUSPECTED ADVERSE REACTIONS to the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

Indications

Dysport for injection is indicated for the treatment of:

  • Cervical dystonia
  • Spasticity in adult patients
  • Lower limb spasticity in pediatric patients 2 years of age and older

Please see Full Prescribing Information, including Boxed Warning and Medication Guide.

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To qualify for our Dysport Doctor Locator, a healthcare professional must meet one or more of the following criteria:
  1. Have ready access to Dysport via discount contract or otherwise
  2. Have participated in Dysport injection training programs or Dysport speaker programs
  3. Have participated in Dysport clinical studies
  4. Have verifiable experience treating patients with Dysport
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